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KMID : 0358320080490070647
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Korean Journal of Urology
2008 Volume.49 No. 7 p.647 ~ p.649
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A Primary Large Cell Neuroendocrine Carcinoma of the Urinary Bladder in a 19-year-old Man
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Kwon Whi-An
Ha Yun-Sok
Lee Ok-Jun
Kim Yong-June
Yun Seok-Joong
Lee Sang-Cheol
Kim Wun-Jae
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Abstract
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Primary large cell neuroendocrine carcinomas of the urinary bladder are extremely rare. To date, only six cases of large cell neuroendocrine carcinoma have been reported. We present a case of a 19-year-old man who presented with gross hematuria and who was subsequently found to have a solitary tumor on the dome of the urinary bladder. The patient underwent transurethral resection of the bladder tumor for histological confirmation. A diagnosis of large cell neuroendocrine carcinoma was made based upon immunohistochemical reactivity for synaptophysin and CD56. Based on the pathologic diagnosis, he subsequently had a partial cystectomy. Histologically, the tumor penetrated the perivesical fat. It has now been 6 months since the surgery, and the patient is preparing to receive his 5th cycle of chemotherapy. There is no evidence of tumor recurrence or metastasis.
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KEYWORD
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Carcinoma, large cell, Neuroendocrine carcinoma, Urinary bladder
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